Type I IL-4Rs Selectively Activate IRS-2 to Induce Target Gene Expression in Macrophages
- 23 December 2008
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science Signaling
- Vol. 1 (51) , ra17
- https://doi.org/10.1126/scisignal.1164795
Abstract
The ability of IL-4, but not IL-13, to efficiently activate IRS-2 leads to the expression of a subset of genes in alternatively activated macrophages.Keywords
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