THE CIRCADIAN RHYTHM OF LH RELEASE CAN BE SHIFTED BY INJECTIONS OF A BENZODIAZEPINE IN FEMALE GOLDEN HAMSTERS
- 1 February 1988
- journal article
- research article
- Published by The Endocrine Society in Endocrinology
- Vol. 122 (2) , 756-758
- https://doi.org/10.1210/endo-122-2-756
Abstract
Three daily injections of the short-acting benzodiazepine, triazolam, induced pronounced phase shifts in the onset of both the circadlan surge in pituitary LH release and the circadian rhythm of locomotor activity in ovariectomized hamsters treated with estrogen. Both the magnitude and the direction of the phase shifts in these two rhythms were similar. These results indicate that a master circadian clock underlying diverse behavioral and endocrine rhythms can be reset by treatment with triazolam.Keywords
This publication has 6 references indexed in Scilit:
- The 24-Hour Profile of Adrenocorticotropin and Cortisol in Major Depressive Illness*Journal of Clinical Endocrinology & Metabolism, 1985
- Multiple Circadian Oscillators Regulate the Timing of Behavioral and Endocrine Rhythms in Female Golden HamstersScience, 1985
- Effects of “Jet Lag” on Hormonal Patterns. IV. Time Shifts Increase Growth Hormone Release*Journal of Clinical Endocrinology & Metabolism, 1983
- Effects of “Jet Lag” on Hormonal Patterns. I. Procedures, Variations in Total Plasma Proteins, and Disruption of Adrenocorticotropin-Cortisol Periodicity*Journal of Clinical Endocrinology & Metabolism, 1981
- Ovarian Steroid Modulation of Gonadotropin Secretion and Pituitary Responsiveness to Luteinizing Hormone-Releasing Hormone in the Female Hamster*Endocrinology, 1978
- Cyclic Gonadotropin Release in the Presence and Absence of Estrogenic Feedback in Ovariectomized Golden HamstersBiology of Reproduction, 1978