Production of a Monoclonal Antibody to T-2 Toxin with Strong Cross-Reactivity to T-2 Metabolites
- 1 January 1987
- journal article
- research article
- Published by Scientific Societies in Phytopathology®
- Vol. 77 (1) , 57-59
- https://doi.org/10.1094/phyto-77-57
Abstract
A monoclonal antibody against T-2 toxin [a trichothecine produced by Fusarium spp.] was produced using a mouse immunized by subcutaneous injections into the shoulder with large immunogen doses. When this antibody was used in an indirect competitive enzyme immunoassay, sensitivity to T-2 toxin was 10 ng/ml (0.5 ng per assay). The antibody cross-reacted less to HT-2 toxin than T-2 antibodies previously described. Strong cross-reaction with the T-2 metabolites 3''OH T-2 and 3''OH HT-2 was noted.Keywords
This publication has 3 references indexed in Scilit:
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