Coagulation Defects and Giant Cavernous Hemangioma
- 1 January 1966
- journal article
- research article
- Published by American Medical Association (AMA) in American Journal of Diseases of Children
- Vol. 111 (1) , 71-74
- https://doi.org/10.1001/archpedi.1966.02090040107013
Abstract
HYPOFIBRINOGENEMIA and associated coagulation defects complicating giant cavernous hemangioma in an infant have been reported rarely.1,2 It is the purpose of this paper to describe such a case. Following radiation therapy the hemangioma regressed and the deficiencies in fibrinogen and other coagulation factors returned to normal. Materials and Methods The bleeding time was performed by the method of Ivy3 and the clotting time by the single tube method of Lewis and Glueck.4 Platelet counts were performed by the method of Dameshek.5 The prothrombin time (ProT) was measured by the method of Quick.6 In one instance the ProT was performed after 0.1 ml of a 1% solution of bovine fibrinogen (Armour) was added to both test and normal plasma. Blood-clotting factor V was measured by the method of Stefanini and Dameshek7; factors VII-X complex were measured by methods previously described.8 Factor VIII was assayedThis publication has 0 references indexed in Scilit: