Effect of L-dopa on dementia-related rigidity
- 1 July 1989
- journal article
- research article
- Published by Hindawi Limited in Acta Neurologica Scandinavica
- Vol. 80 (1) , 64-67
- https://doi.org/10.1111/j.1600-0404.1989.tb03844.x
Abstract
‐ L‐dopa 100 mg plus benserazide 25 mg versus placebo were given 3 times daily to 14 consecutive patients with dementia and rigidity. The treatment was crossed over to the alternative therapy after a 7‐day period. Despite a mean 60% raise in CSF‐HVA during L‐dopa administration, no patient responded to the treatment. These data suggest that dementia‐associated rigidity differs, at least, pharmachologically from parkinsonian rigidity.Keywords
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