Interplay between Ras‐related and heterotrimeric GTP binding proteins: lifestyles of the BIG and little 1

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Abstract
Directed interactions of heterotrimeric G-proteins coupled to receptors responding to extracellular signals and small Ras-related GTPases that control a variety of intracellular processes are being elucidated by recent work. We explore two of the most well-characterized pathways that couple big G-proteins to their smaller relatives.

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