In 19 of the 20 cases of Hurler's syndrome reported in the literature bilateral corneal cloudiness has been observed. Recently, 2 children, brother and sister, aged 5 years and 7 months, respectively, were referred for examination to the ophthalmologic clinic of the New York Hospital by the staff of Dr. S. Z. Levine of the department of pediatrics. A third patient, a boy of 6 years of age, was seen in Dr. Bernard Samuels' service at the New York Eye and Ear Infirmary. The eyes of all 3 children were examined with the slit lamp. The first patient (R. M., fig. 1) died after an operation performed to repair an umbilical hernia, and autopsy was performed. This case will be reported in full by the department of pediatrics of New York Hospital. At autopsy I was fortunate in obtaining one of the eyes from this child for histologic examination. Gertrude