Muscle Glycogen Fractions During Stimulation

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Abstract
A gastrocnemius muscle of a rat was contracted isometrically in response to stimuli. The contralateral muscle was used as a control. Stimulation was continued until the tension had dropped to either 90/50 or 10% of peak tension. After various periods of stimulation it was found that during the first few sec. of stimulation only acid extractable glycogen disappeared and that as stimulation continued both acid and alkali soluble fractions begin to be lost at approx. the same rate. This is interpreted to mean that the acid-extractable portion of the total muscle glycogen is, physiologically, the more labile moiety.

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