Dynamic Positron Emission Tomography for Study of Cerebral Hemodynamics in a Cross Section of the Head Using Positron-Emitting 68Ga-EDTA and 77Kr

Abstract
Dynamic positron emission tomographic studies were performed on over 120 patients with occlusive cerebrovascular disease, arteriovenous malformations and brain tumors using the positron section scanner, consisting of a ring of 32 scintillation detectors. The radiopharmaceuticals were nondiffusible 68Ga-EDTA for transit time and uptake studies and the diffusible tracer 77Kr for quantitative regional cerebral blood flow studies in every cm2 of the cross section of the head. The results of dynamic positron emission tomography in correlation with the results from the .gamma. scintillation camera dynamic studies and computed tomography (CT) scans are discussed.