Water Content in Human Intervertebral Discs

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Abstract
Water content of intervertebral discs is a significant aspect of both viscoelastic behavior and age-related degenerative changes. Using water content as a dependent variable, stress-relaxation was measured using standardized anulus fibrosus specimens strained at various levels of strain. Synthesis of experimental data into a master relaxation curve allows prediction of specimen response over time intervals not readily accessible experimentally. A quantitative understanding of the role water content may have important clinical application, since magnetic resonance imaging is a tool which should allow water content determination in vivo.

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