ALGORITHM FOR EXTRACORPOREAL BLOOD-GLUCOSE REGULATION

  • 1 January 1979
    • journal article
    • research article
    • Vol. 17  (7) , 465-469
Abstract
A control mechanism is described, based on a simple proportional/differential regulation. The calculation takes 1 min. and it takes into account glucose degradation, insulin half life in vivo, and the delay between blood sampling and insulin action on the blood glucose value [in humans]. This is repeated continuously every minute (short time mode) or every 5 min. or more (long time mode), depending on the rate of change of the blood glucose. Operator decision is based on digitally converted tables, which are analogous to the graph of proportional control, and on glucose equivalent tables, which give the insulin effect on glucose as a function of time.

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