GENERALIZED URTICARIA WITH ELECTROCARDIOGRAPHIC CHANGES SIMULATING MYOCARDIAL INFARCTION

Abstract
A review of the literature reveals that acute cardiac manifestations in association with urticaria are uncommon; however, it has been observed that definite cardiac changes may accompany allergic reactions. The report of the following case illustrates electrocardiographic changes simulating myocardial infarction that occurred during the course of urticaria. REPORT OF A CASE History.— A white woman, 65, entered Providence Hospital on April 13, 1946, with the complaint of shortness of breath and hives. For the preceding two weeks her family physician had treated her with intravenously administered "cincosal" (sodium cinchophen, 1 gm., sodium salicylate, 1 gm., and sodium iodide, 0.5 gm., in 20 cc.) for arthritis. The contraindications to the use of "cincosal" are stated to be impaired heart action, syphilis, liver impairment or susceptibility to liver disease, tuberculosis, or thyroid disease. This was the only medication. Seven days before admission she noted itching of the scalp followed by

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