POTASSIUM OUTFLUX FROM RABBIT CORTEX DURING SPREADING DEPRESSION

Abstract
The time course of K outflux from the exposed intact rabbit cortex was found to be the same as that of the negative slow potential change associated with spreading depression. The magnitude of the K outflux during spreading depression approaches that obtained at postmortem and bears a roughly linear relationship to the maximum DC potential changes developed during a spreading depression. The relationships of these data to some current concepts of the mechanism of spreading depression propagation are discussed.

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