Neurologic findings in men with isolated hypogonadotropic hypogonadism
- 1 February 1989
- journal article
- research article
- Published by Wolters Kluwer Health in Neurology
- Vol. 39 (2) , 223
- https://doi.org/10.1212/wnl.39.2.223
Abstract
We studied the neurologic abnormalities in 41 men with isolated hypogonadotropic hypogonadism. Findings included anosmia, hyposmia, mirror movements, ocular motor abnormalities, cerebellar dysfunction, and pes cavus foot deformity. One-third of the subjects had a family history of delayed sexual maturation. Patients with a family history of delayed sexual maturation had a significantly higher incidence of olfactory dysfunction, mirror movements, and pes cavus foot deformity. Our data suggest that isolated hypogonadotropic hypogonadism and its accompanying neurologic abnormalities may arise from a genetically linked developmental abnormality of CNS structures.This publication has 14 references indexed in Scilit:
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