VARIATIONS OF PLASMA CORTISOL AND BLOOD FIBRINOLYTIC ACTIVITY DURING ANAESTHETIC AND SURGICAL STRESS
Open Access
- 1 December 1972
- journal article
- research article
- Published by Elsevier in British Journal of Anaesthesia
- Vol. 44 (12) , 1291-1297
- https://doi.org/10.1093/bja/44.12.1291
Abstract
Blood fibrinolytic activity and plasma cortisol levels were investigated during surgical procedures in twenty-three patients who underwent laparotomy. From 30 minutes to 1½ hours of surgical stress, enhancement of fibrinolysis was significantly correlated with increase of plasma cortisol levels. There were no exceptions to this pattern. The changes in fibrinolytic activity and plasma cortisol levels were found to depend mainly on the surgical stress. There was no difference with regard to the various anaesthetics employed.Keywords
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