A microinjected monoclonal antibody against human DNA polymerase-alpha inhibits DNA replication in human, hamster, and mouse cell lines.
Open Access
- 1 August 1986
- journal article
- research article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 261 (23) , 10802-10807
- https://doi.org/10.1016/s0021-9258(18)67458-7
Abstract
No abstract availableThis publication has 37 references indexed in Scilit:
- Co-operation between the p53 protein tumor antigen and platelet-poor plasma in the induction of cellular DNA synthesisExperimental Cell Research, 1986
- Inhibition of DNA replication and DNA polymerase .alpha. activity by monoclonal anti-(DNA polymerase .alpha.) IgG and F(ab) fragmentsBiochemistry, 1985
- Expression of the p53 protein during the cell cycle of human peripheral blood lymphocytesExperimental Cell Research, 1985
- Cellular DNA replication is independent of the synthesis or accumulation of ribosomal RNAExperimental Cell Research, 1984
- Catalytic function of thymidylate synthase is confined to S phase due to its association with replitaseBiochemical and Biophysical Research Communications, 1982
- Induction of cell DNA replication in G1-specific ts mutants by microinjection of SV40 DNAExperimental Cell Research, 1981
- Intracellular neutralization of SV40 tumor antigens following microinjection of specific antibodyCell, 1980
- Antibodies introduced into living cells by red cell ghosts are functionally stable in the cytoplasm of the cellsCell, 1979
- Degradation of proteins microinjected into cultured mammalian cellsJournal of Cellular Physiology, 1979
- A temperature‐sensitive cell cycle mutant of the BHK cell lineJournal of Cellular Physiology, 1974