Comparison of Intracellular PO2 and Conditions for Blood-Tissue O2 Transport in Heart and Working Red Skeletal Muscle

Recent measurements (Honig et al., 1984; Gayeski, Connett and Honig, 1985; Gayeski and Honig, 1986) and mathematical models (Hellums, 1977; Clark et al., 1985; Federspiel and Popel, in press; Groebe and Thews, 1986) indicate that the principal resistance to O₂ mass transfer is at the capillary under conditions of high O₂ flux. Federspiel and Popel (in press) have described this behaviour by relating the transcapillary O₂ flux to a driving force. The factor of proportionality is a mass transfer coefficient homologous to a conductance: 1 $$J=C\times\left[Pcap{{O}_{2}}-Pcell{{O}_{2}}\right]$$