Influence of thyroid status on the membranes of rat liver mitochondria Unique localization of L‐glycerol‐3‐phosphate dehydrogenase
- 30 January 1989
- journal article
- Published by Wiley in FEBS Letters
- Vol. 243 (2) , 247-250
- https://doi.org/10.1016/0014-5793(89)80138-3
Abstract
The effect of thyroid status on the physical properties of rat liver mitochondrial membranes and on the lipid microenvironment of proteins was investigated. The steady‐state fluorescence anisotropy of diphenyl‐1,3,5‐triene and 1‐[4‐{trimethylaminophenyl} phenyl]‐6‐phenylhexa‐1,3,5‐triene revealed an increase of the order of the membranes with the increase of hormone level. Protein arrangement in the inner mitochondrial membrane altered with the thyroid status, which was reflected by digitonin subfractionation of mitochondria. The microenvironment of FAD‐linked L‐glycerol‐3‐phosphate dehydrogenase was dramatically influenced by thyroxine.Keywords
This publication has 26 references indexed in Scilit:
- Lateral segregation of sterol and channel proteins in the mitochondrial outer membrane induced by phospholipase A2: Evidence from negative-stain electron microscopy using filipinJournal of Ultrastructure and Molecular Structure Research, 1988
- Regulation of glycerol 3‐phosphate oxidation in mitochondria by changes in membrane microviscosityFEBS Letters, 1986
- Enrichment and biochemical characterization of boundary membrane contact sites from rat-liver mitochondriaBiochimica et Biophysica Acta (BBA) - Biomembranes, 1986
- The induction of mitochondrial l -3-glycerophosphate dehydrogenase by thyroid hormoneBiochimica et Biophysica Acta (BBA) - Bioenergetics, 1986
- Plasma membrane fluidity measurements on whole living cells by fluorescence anisotropy of trimethylammoniumdiphenylhexatrieneBiochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1985
- Membrane lipid fluidity and its effect on the activation energy of membrane-associated enzymesBiochimica et Biophysica Acta (BBA) - Biomembranes, 1979
- Protein‐lipid interactionsFEBS Letters, 1979
- The use of the fluorescent probe α-parinaric acid to determine the physical state of the intracytoplasmic membranes of the photosynthetic bacterium, Rhodopseudomonas sphaeroidesBiochimica et Biophysica Acta (BBA) - Biomembranes, 1978
- The influence of thyroid hormones on the structure and function of mitochondrial membranesBiochimica et Biophysica Acta (BBA) - Biomembranes, 1976
- AN ELECTRON-TRANSPORT SYSTEM ASSOCIATED WITH THE OUTER MEMBRANE OF LIVER MITOCHONDRIAThe Journal of cell biology, 1967