Reduced Recovery of Dieldrin Residues—A Shortcoming of Sulfuric Acid Cleanup of Biological Samples
- 1 May 1981
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Analytical Toxicology
- Vol. 5 (3) , 150-152
- https://doi.org/10.1093/jat/5.3.150
Abstract
Reduced quantitative recovery of dieldrin (1,2,3,4,10,10-hexachloro-6,7-epoxy-1,4,4a,5,6,7,8,8a-octahydro-1,4-endo, exo-5,8-dimethanonaphthalene) while using concentrated sulfuric acid for the cleanup of the extracted samples, has been investigated by gas-liquid chromatography and infrared (IR) spectroscopy. In vitro studies have shown that the servere breakdown in the recovery of dieldrin can be checked if 65% (v/v) H2SO4 is used as opposed to the concentrated H2SO4. Infrared studies revealed that at concentrations > 70% sulfuric acid, the epoxide ring attached to the norbornene nucleus of dieldrin undergoes rearrangement to form keto-dihydroaldrin.This publication has 5 references indexed in Scilit:
- Organochlorine Pesticides in Specimens from Women Undergoing Spontaneous Abortion, Premature or Full-Term DeliveryJournal of Analytical Toxicology, 1981
- Organochlorine Compounds (DDT, Hexachlorocyclohexane, Hexachlorobenzene) in Icelandic Animal Body Fat and Butter Fat: Local and Global Sources of ContaminationActa Pharmacologica et Toxicologica, 1979
- SIMPLIFIED FAT EXTRACTION WITH SULFURIC-ACID AS CLEANUP PROCEDURE FOR RESIDUE DETERMINATION OF CHLORINATED HYDROCARBONS IN BUTTER1978
- STUDY OF PESTICIDE-RESIDUES IN MICHIGANS GENERAL POPULATION, 1968-701977
- A rapid analytical method for persistent pesticides in proteinaceous samplesBulletin of Environmental Contamination and Toxicology, 1966