Heterogeneity of Schizophrenia
- 2 January 1990
- journal article
- review article
- Published by Royal College of Psychiatrists in The British Journal of Psychiatry
- Vol. 156 (1) , 17-26
- https://doi.org/10.1192/bjp.156.1.17
Abstract
Schizophrenia is clinically heterogeneous but it is not known whether this is due to the existence of discrete subtypes. For the purpose of explication, ‘indicators' of schizophrenia are divided into three levels: phenomenology, pathophysiology, and aetiology. Five heterogeneity models and a number of quantitative approaches are described. It is imperative to apply rigorous methods of study to the comparison of unitary models and competing heterogeneity models of schizophrenia.Keywords
This publication has 33 references indexed in Scilit:
- Splitting schizophreniaNature, 1988
- Evidence against linkage of schizophrenia to markers on chromosome 5 in a northern Swedish pedigreeNature, 1988
- Localization of a susceptibility locus for schizophrenia on chromosome 5Nature, 1988
- Is There Really A Split in Schizophrenia?The British Journal of Psychiatry, 1987
- Early Neuroleptic ResponseJournal of Clinical Psychopharmacology, 1987
- Ventricular Enlargement in SchizophreniaThe British Journal of Psychiatry, 1985
- IS SCHIZOPHRENIA AN INFECTIOUS DISEASE?The Lancet, 1983
- Plots of High-Dimensional DataPublished by JSTOR ,1972
- Schizophrenia: Evidence for the major gene hypothesisBehavior Genetics, 1970
- Genetical causes of schizophrenic symptomsEuropean Neurology, 1947