Nip and tuck at the neuromuscular junction: A role for proteases in developmental synapse elimination
- 1 April 1997
- Vol. 19 (4) , 271-275
- https://doi.org/10.1002/bies.950190402
Abstract
During late embryonic and early postnatal development, synaptic connections are extensively modified so that some functional connections are weakened and eliminated from a neural circuit while others are strengthened and maintained. The mechanisms that underlie synapse elimination are beginning to be understood from studies of the neuromuscular junction. A recent paper(1) provides some intriguing insights into the role proteases may play in the developmental disassembly of neuromuscular synapses.Keywords
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