Thrombophilia as a predictor of persistent residual vein thrombosis
- 1 March 2008
- journal article
- Published by Ferrata Storti Foundation (Haematologica) in Haematologica
- Vol. 93 (3) , 479-480
- https://doi.org/10.3324/haematol.12205
Abstract
To compare the probability of leg vein recanalization between carriers and non-carriers of thrombophilia after an episode of deep vein thrombosis (DVT) of the lower extremities, we reviewed the clinical records of 472 patients with proximal DVT who were diagnosed with thrombophilia, and had long-term ultrasound scanning. One hundred and thirty-seven patients (29.0%) were carriers of thrombophilia. After adjusting for age, sex, DVT localization and modality of presentation, the hazard ratio of vein recanalization in thrombophilic compared with non-thrombophilic patients was 0.49 (95% CI, 0.38 to 0.63). These findings suggest that thrombophilia is an independent predictor of persistent residual vein thrombosis.Keywords
This publication has 4 references indexed in Scilit:
- The risk of recurrent venous thromboembolism among heterozygous carriers of factor V Leiden or prothrombin G20210A mutation. A systematic review of prospective studiesHaematologica, 2007
- The Pathogenesis of Venous Thromboembolism: Evidence for Multiple Interrelated CausesAnnals of Internal Medicine, 2006
- Post‐treatment residual thrombus increases the risk of recurrent deep vein thrombosis and mortalityJournal of Thrombosis and Haemostasis, 2006
- Residual Venous Thrombosis as a Predictive Factor of Recurrent Venous ThromboembolismAnnals of Internal Medicine, 2002