The use of a retroviral vector to identify foetal striatal neurones transplanted into the adult striatum
- 1 January 1990
- journal article
- research article
- Published by Springer Nature in Experimental Brain Research
- Vol. 79 (2) , 427-435
- https://doi.org/10.1007/bf00608254
Abstract
A retrovirus which encodes β-galactosidase was used to infect embryonic rat striatal cells before grafting these cells into the lesioned adult rat striatum. Examination of the grafts after long term survival (8 months) revealed that a few small and large cells expressed large amounts of bacterial β-galactosidase activity. The larger diameter cells were identified as neurones by their size, shape and presence of neuronal processes. The identity of the small diameter cell types was not established.Keywords
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