Control of Granulocytes and Macrophages: Molecular, Cellular, and Clinical Aspects

25 October 1991

journal article
review article
Published by American Association for the Advancement of Science (AAAS) in Science

Vol. 254 (5031) , 529-533
https://doi.org/10.1126/science.1948028

Abstract

The production and functional activity of two important white blood cells, the granulocytes and macrophages, are regulated mainly by a group of glycoprotein colony-stimulating factors. The colony-stimulating factors have been mass-produced with recombinant technology and are now proving of value in preventing or suppressing infections in a variety of individuals with subnormal or defective formation of blood cells.

Keywords

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