Depot Antipsychotics in the Prophylaxis of Bipolar Affective Disorder
- 1 December 1994
- journal article
- Published by Royal College of Psychiatrists in The British Journal of Psychiatry
- Vol. 165 (6) , 827-829
- https://doi.org/10.1192/bjp.165.6.827
Abstract
Background: The efficacy of depot antipsychotic drugs in the prophylaxis of bipolar affective disorder was investigated.Method: Life charts were constructed for 18 outpatients with bipolar disorder receiving prophylactic treatment with depot medication. The durations of affective episodes were compared during periods on or off medication.Results: The subjects suffered fewer relapses and spent significantly less time in hospital (P = 0.001) for treatment of manic, depressive and mixed affective illness during treatment with depot antipsychotics.Conclusions: Depot antipsychotic medication may be a useful prophylactic treatment for certain patients with bipolar affective disorder.British Journal of Psychiatry (1994), 165, 827–829Keywords
This publication has 8 references indexed in Scilit:
- Depot antipsychotics in bipolar affective disorderInternational Clinical Psychopharmacology, 1993
- Adherence to Lithium Prophylaxis: I. Clinical Predictors and Patient's Reasons for NonadherencePharmacopsychiatry, 1988
- Comparison of the Prophylactic Action of Flupenthixol with Placebo in Lithium Treated Manic-Depressive PatientsThe British Journal of Psychiatry, 1986
- Five to Fifteen Years?? Maintenance Doxepin TherapyInternational Clinical Psychopharmacology, 1986
- Flupenthixol decanoate in recurrent manic‐depressive illnessActa Psychiatrica Scandinavica, 1981
- Depot Injections for Affective DisordersThe British Journal of Psychiatry, 1980
- Prophylactic Efficacy of Lithium Carbonate in Manic-Depressive IllnessArchives of General Psychiatry, 1973
- PROPHYLACTIC LITHIUM IN AFFECTIVE DISORDERSThe Lancet, 1971