Quantitative acoustical assessment of wound maturation with acoustic microscopy

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Abstract
Ultrasonic characterization of cutaneous wound tissue and surrounding margin in dogs with the scanning laser acoustic microscope showed an increase in the speed of sound and in the acoustic heterogeneity as a function of wound age. As the wound age increased, the wound area, initially quite homogeneous in acoustic appearance, became more heterogeneous; the acoustic appearance of the wound tended to become similar to the adjacent tissue; and the ultrasonic velocity of the wound area increased from a range of 1540-1575 m/s at 7 days to 1700-2000 m/s at 35 days.

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