Dermal and Respiratory Exposure to Applicators and Occupants of Residences Treated with Dichlorvos (DDVP)

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Abstract
Single-family residences were treated with a 0.5% (AI) solution of dichlorvos (DDVP) to control Blattella germanica (L.). Pesticide applicators and residents of treated structures were monitored for evidence of DDVP exposure with exposure pads, air samplers, serum and erythrocyte acetylcholinesterase tests, and urinalyses. Toxic doses were 0.028%/h for applicators and 0.030%/h for residents who were present during application and remained in the treated structure for 24 h after treatment. There was no evidence of DDVP or the dichloracetic acid metabolite in the urine of the applicators or residents. There were slight but statistically significant differences in serum acetylcholinesterase activity of residents of treated structures, but erythrocyte acetylcholinesterase was unchanged. We concluded that there was not a significant risk, in terms of acute toxicity, to either the pesticide applicators or the residents of treated structures when DDVP was used for cockroach control.