SNP discovery using advanced algorithms and neural networks

Open Access

3 March 2005

journal article
research article
Published by Oxford University Press (OUP) in Bioinformatics

Vol. 21 (10) , 2528-2530
https://doi.org/10.1093/bioinformatics/bti354

Abstract

Summary: Forage is an application which uses two neural networks for detecting single nucleotide polymorphisms (SNPs). Potential SNP candidates are identified in multiple alignments. Each candidate is then represented by a vector of features, which is classified as SNP or monomorphic by the networks. A validated dataset of SNPs was constructed from experimentally verified SNP data and used for network training and method evalutation. Availability: The package is available at biobase.biotech.kth.se/forage/ Contact:fredrik@biotech.kth.se Supplementary information: Additional results and method description can be found at biobase.biotech.kth.se/forage/

Keywords

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