Compression of Microcapsules I: Effect of Excipients and Pressure on Drug Release
- 1 January 1989
- journal article
- research article
- Published by Taylor & Francis in Drug Development and Industrial Pharmacy
- Vol. 15 (12) , 2049-2053
- https://doi.org/10.3109/03639048909052518
Abstract
Microcapsules containing phenylpropanolamine-resin complexes were compressed with various diluents. Compression of microcapsules produced an increase in the release rate. An average reduction of 0.50 hours was observed when Emdex or Fast Flo Lactose were compared to Avicel at various pressures (35 to 281 MPa). Increasing the amount of microcapsules in the formulation reduced the T50% with all three diluentsThis publication has 7 references indexed in Scilit:
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