Monitoring oral anticoagulation in primary care

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Abstract
The purpose of oral anticoagulant treatment is to decrease thrombotic episodes, particularly stroke, by interfering with the haemostatic pathways.3 The intensity of anticoagulant effect required for any particular indication remains controversial.4 There have been problems in standardising test results between different centres at local and international levels. Data showing wide international variation in mean warfarin doses—Hong Kong under 2 mg, North America over 8 mg, and British figures between these extremes5—led to international collaboration to improve testing and …