A new hamster model for adenoviral vaccination
- 1 September 1988
- journal article
- research article
- Published by Springer Nature in Archiv für die gesamte Virusforschung
- Vol. 100 (3-4) , 279-283
- https://doi.org/10.1007/bf01487691
Abstract
Both adult and baby hamsters infected intranasally with human adenovirus type 5 exhibited virologic, serologic, and histologic evidence of infection. When 8-day old hamsters were infected with 4×106 pfu, concentrations of virus up to 2×106 pfu/animal were detected in the lung, peaking on day 2. The minimum infectious dose was 1×103 pfu/animal. This model may be useful in studies of conventional and recombinant adenoviral vaccines for humans.This publication has 12 references indexed in Scilit:
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