ESTROGENIC OINTMENTS

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Abstract
THISe whether any changes in the skin could be produced by topical application of hormonecontaining ointments. MATERIALS AND METHODS The study was conducted on 36 persons, of whom 30 were men and 6 women. Group 1A.— This group consisted of 9 postmenopausal women, most of whom fell into a rather advanced age group, that from 51 to 79 years. Group 1B.— This group consisted of 5 men, all over 55 years of age. These two groups were treated in an identical manner with an ointment containing 7,500 international units per ounce (242 international units per gram), as follows: Beneath each scapula a 10 by 10 cm. area was marked out as the test area. On one side a 4 Gm. portion of the ointment, containing a total of approximately 960 international units of estrogens, was spread over the test area and covered with a square of glassine® paper. Over this

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