Specificity of Amino Acid Transport in Trypanosoma equiperdum*
- 1 May 1974
- journal article
- Published by Wiley in The Journal of Protozoology
- Vol. 21 (2) , 368-373
- https://doi.org/10.1111/j.1550-7408.1974.tb03672.x
Abstract
SYNOPSIS: Uptake of [14C] alanine, arginine, glutamic acid and phenylalanine by Trypanosoma equiperdum occurred by both a mediated mechanism and diffusion. Twenty amino acids were studied as inhibitors of absorption of the above amino acids. Results suggested that at least 4 distinct transport loci are involved in amino acid transport. These 4 loci have overlapping affinities for amino acids and seem to be involved, respectively, in the absorption of (a) arginine and phenylalanine; (b) arginine; (c) alanine, phenylalanine, and glutamic acid; (d) glutamic acid. The data also showed that multiple sites for substrate binding occur on each of 2 transport systems.Keywords
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