INVESTIGATIONS ON TOXOPLASMA SPECIFIC IGM-ANTIBODIES COMPARISON OF ISAGA (IMMUNOSORBENT AGGLUTINATION ASSAY AND IMMUNOFLUORESCENCE RESULTS

  • 1 January 1985
    • journal article
    • research article
    • Vol. 189  (2) , 73-78
Abstract
Serum samples from 702 persons were examined for Toxoplasma-specific IgM-antibodies using the immunosorbent agglutination assay (ISAGA) and the immunofluorescence-test (IIFT). Samples (250) showed a positive reaction in the Sabin-Feldman-test (SFT) with titers .gtoreq. 1:1024, 58% were positive in ISAGA and 36% in the IIFT. Samples of persons with acute Toxoplasma-infection, showed high titers in the ISAGA and SFT as well, even in cases where the IgM-IIFT was negative. SFT-negative sera and others with weakly-positive reactions and also rheuma-positive samples were negative in the ISAGA. The duration of the Toxoplasma infection was determined by applying the ISAGA in combination with other antibody tests.