A MODEL OF THE HAEMODYNAMIC ACTION OF CARDIOTONICS
- 1 February 1980
- journal article
- research article
- Published by Emerald Publishing in Kybernetes
- Vol. 9 (2) , 133-140
- https://doi.org/10.1108/eb005550
Abstract
Major cardiotonics are now widely used in reviving patients and we are concerned with shock following cardiac surgery. It is, however, difficult to use the most efficient of them, e.g. isoprenalin, with required accuracy regarding its effects. We describe a model which simulates the haemodynamic response to variable doses of cardiotonics. Firstly, one has to identify the parameters of this model and to test it on experimental data. Then one has to use the resulting model in the frame of optimal control of time‐dependent systems in order to determine some doses nearest the optimum.This publication has 1 reference indexed in Scilit:
- Usefulness and limitations of the rate of rise of intraventricular pressure (dp/dt) in the evaluation of myocardial contractility in man∗The American Journal of Cardiology, 1969