New Perspectives On Catalytic Antibodies
- 1 March 1991
- journal article
- review article
- Published by Springer Nature in Nature Biotechnology
- Vol. 9 (3) , 258-262
- https://doi.org/10.1038/nbt0391-258
Abstract
This review will give examples of the structure-function relationships used in the design of catalytic antibodies, including not only ligand or hapten-based approaches but also recent developments in the generation of catalytic antibodies through protein engineering. Last, a thermodynamic analysis is presented, which confirms that some antibodies do indeed catalyze their transformations by stabilizing transition states.Keywords
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