Heparin Treatment of Intravascular Coagulation Accompanying Hemolytic Transfusion Reactions

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Abstract
Two patients with disseminated intravascular coagulation secondary to incompatible blood transfusion are reported. In one, the antibody responsible for the incompatibility was a noncomplement‐dependent anti‐Fya. Intravascular coagulation may be more frequent than has been appreciated, hence, laboratory study of hemostasis should be a part of the evaluation of patients who have received incompatible blood. Prompt diagnosis along with heparin therapy may prevent the development of a generalized bleeding diathesis.