(5R,8S,10R)-6-Alkyl-8-ergolinecarboxylic acids and some of their derivatives
- 1 January 1983
- journal article
- Published by Institute of Organic Chemistry & Biochemistry in Collection of Czechoslovak Chemical Communications
- Vol. 48 (5) , 1483-1488
- https://doi.org/10.1135/cccc19831483
Abstract
(5R,8S,10R)-6-Methyl-8-methoxycarbonylergoline (VIIb) was converted via Ib and IIb into its 6-analogues IIIb-VIb, which, in turn, were converted into acids IIIa-VIa and hydrazides IIIc-VIc. Some of the esters prepared, mainly IVb, had inhibitory effects on the secretion of prolactin in rats.Keywords
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