Evaluation of Five Serologic Tests for Antibody to Neisseria gonorrhoeae

Abstract
Sera from 1167 [human] individuals were tested for antibody [Ab] to N. gonorrhoeae by use of 5 different serologic tests. These were complement fixation, the indirect fluorescent Ab test, Gonosticon Dri-Dot, fluorescent gonorrhea test-heated and gonorrhea screen test. Parallel cultures of material from the throat, urethra, cervix and rectum were done. The results were analyzed by a technique intended to separate test effects from population effects. Test specificities ranged from 81.3% for the Dri-Dot test to 96.1% for the indirect fluorescent Ab test. Sensitivities ranged from 55.6% for the Dri-Dot test to 81.5% for the fluorescent gonorrhea test-heated.

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