Abstract
Stereospecific rearrangement of the ionophore antibiotic X-14547A (indanomycin) and related derivatives, occurs readily at 70 °C in acetonitrile solution containing lithium tetrafluoroborate. The product of the reaction is a novel tetracyclic compound derived by ring cleavage of the tetrahydropyranyl ring, with concomitant double-bond migration and intramolecular cyclisation involving a pyrrole group.

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