Improved Nutrient Absorption after Cimetidine in Short-Bowel Syndrome with Gastric Hypersecretion
- 11 January 1979
- journal article
- case report
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 300 (2) , 79-80
- https://doi.org/10.1056/nejm197901113000207
Abstract
MODERATE gastric hypersecretion is not uncommon after massive small-bowel resection,1 though it may be temporary.2 We speculated that, in patients with the short-bowel syndrome, increased duodenal acid and volume loads might impair digestion and absorption in the proximal gut. Cimetidine, a potent gastric antisecretory agent, might partially correct these abnormalities, allowing for greater efficiency of intraluminal digestion. The following studies in a patient with the short-bowel syndrome lend support to that speculation.Material and Methods Case report. A 36-year-old woman was seen because of massive steatorrhea (excretion of 18 g per day on a 20-g-fat diet), diarrhea (10 to . . .Keywords
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