TNFα blockade in rheumatoid arthritis: Rationale, clinical outcomes and mechanisms of action
- 28 February 1995
- journal article
- review article
- Published by Elsevier in International Journal of Immunopharmacology
- Vol. 17 (2) , 141-145
- https://doi.org/10.1016/0192-0561(94)00092-3
Abstract
No abstract availableKeywords
This publication has 13 references indexed in Scilit:
- Chronic exposure to tumor necrosis factor (TNF) in vitro impairs the activation of T cells through the T cell receptor/CD3 complex; reversal in vivo by anti-TNF antibodies in patients with rheumatoid arthritis.Journal of Clinical Investigation, 1994
- New Directions for Biological Therapy in Rheumatoid ArthritisInternational Archives of Allergy and Immunology, 1994
- Treatment of rheumatoid arthritis with chimeric monoclonal antibodies to tumor necrosis factor αArthritis & Rheumatism, 1993
- Construction and initial characterization of a mouse-human chimeric anti-TNF antibodyMolecular Immunology, 1993
- Localization of tumor necrosis factor receptors in the synovial tissue and cartilage‐pannus junction in patients with rheumatoid arthritis. Implications for local actions of tumor necrosis factor αArthritis & Rheumatism, 1992
- Increased levels of soluble tumor necrosis factor receptors in the sera and synovial fluid of patients with rheumatic diseasesArthritis & Rheumatism, 1992
- Acceleration of onset of collagen-induced arthritis by intra-articular injection of tumour necrosis factor or transforming growth factor-betaClinical and Experimental Immunology, 1992
- The Pathophysiology of Tumor Necrosis FactorsAnnual Review of Immunology, 1992
- Localization of Tumor Necrosis Factor α in Synovial Tissues and at the Cartilage–Pannus Junction in Patients With Rheumatoid ArthritisArthritis & Rheumatism, 1991
- INHIBITORY EFFECT OF TNF$alpha; ANTIBODIES ON SYNOVIAL CELL INTERLEUKIN-1 PRODUCTION IN RHEUMATOID ARTHRITISThe Lancet, 1989