• 1 January 1980
    • journal article
    • research article
    • Vol. 55  (1) , 51-53
Abstract
Because of evidence in experimental animals [chick] that prolactin stimulates production of 1,25-dihydroxyvitamin D, several indices of Ca metabolism were evaluated in patients who had hyperprolactinemia due to functioning pituitary adenomas and in normal age-matched controls. Plasma levels of 1,25-dihydroxyvitamin D in hyperprolactinemic patients were in the normal range (15-24 pg/ml vs. 15-75 pg/ml in controls). Intestinal absorption of Ca, plasma levels of immunoreactive parathyroid hormone and serum values for Ca, P and alkaline phosphatase were similar in patients and controls. Prolactin probably has no effect on plasma 1,25-dihydroxyvitamin D levels or Ca metabolism in man.

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