Branched-chain amino acid biosynthesis genes in Lactococcus lactis subsp. lactis
Open Access
- 1 October 1992
- journal article
- Published by American Society for Microbiology in Journal of Bacteriology
- Vol. 174 (20) , 6580-6589
- https://doi.org/10.1128/jb.174.20.6580-6589.1992
Abstract
The genes for biosynthesis of the branched-chain amino acids leucine, isoleucine, and valine in Lactococcus lactis subsp. lactis NCDO2118 were characterized by cloning, complementation in Escherichia coli and Bacillus subtilis, and nucleotide sequence analysis. Nine structural genes are clustered on a 12-kb DNA fragment in the order leuABCD ilvDBNCA. Upstream of these genes, the nucleotide sequence suggests the existence of regulation by transcriptional attenuation. Between the leuD and ilvD genes is an unexpected gene, encoding a protein which belongs to the ATP-binding cassette protein superfamily.Keywords
This publication has 68 references indexed in Scilit:
- Gene expression in Lactococcus lactisFEMS Microbiology Letters, 1992
- Proteolytic enzymes of dairy starter culturesFEMS Microbiology Letters, 1987
- Gene cloning and expression in lactic streptococciFEMS Microbiology Letters, 1987
- A family of related ATP-binding subunits coupled to many distinct biological processes in bacteriaNature, 1986
- The nodI gene product of Rhizobium leguminosarum is closely related to ATP-binding bacterial transport proteins; nucleotide sequence analysis of the nodI and nodJ genesGene, 1986
- Genetic and physical analysis of the ilvBC-leu region in Bacillus subtilisGene, 1984
- Nucleotide sequence of yeast LEU2 shows 5′-noncoding region has sequences cognate to leucineCell, 1982
- ATTENUATION IN AMINO ACID BIOSYNTHETIC OPERONSAnnual Review of Genetics, 1982
- Control of leu operon expression in Escherichia coli by a transcription attenuation mechanismJournal of Molecular Biology, 1981
- A general method applicable to the search for similarities in the amino acid sequence of two proteinsJournal of Molecular Biology, 1970