Isolation and structure of the powerful human cancer cell growth inhibitors spongistatins 4 and 5 from an African Spirastrella spinispirulifera(porifera)
- 1 January 1993
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 24,p. 1805-1807
- https://doi.org/10.1039/c39930001805
Abstract
The Southwest Indian Ocean marine sponge Spirastrella spinispirulifera has been found to contain (in 10–7% yields) two extraordinarily potent (Gl50ca. 10–8µg ml–1) human cancer cell line inhibitors designated spongistatins 4 1d and 5 2.Keywords
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