Transposition of a Gene Encoding OXA-2 -Lactamase
- 1 September 1983
- journal article
- research article
- Published by Microbiology Society in Microbiology
- Vol. 129 (9) , 2951-2957
- https://doi.org/10.1099/00221287-129-9-2951
Abstract
Summary: A bla gene encoding OXA-2 β-lactamase has been transposed from the Salmonella typhimurium R plasmid R1767. This transposable element which was designated Tn2410 encoded sulphonamide and mercury resistance in addition to the bla gene. It had a size of 18.5 kb and appeared to be flanked by small inverted repeats. Restriction enzyme analysis resulted in a detailed map of Tn2410, which showed a high degree of similarity with the published map of Tn2603, a transposon encoding OXA-1 β-lactamase. The ampicillin and sulphonamide resistance genes on Tn2410 were mapped in a cluster on the region between the centre and the right end of the map.This publication has 15 references indexed in Scilit:
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