Certain Biological Characteristics of Adenovirus Types 5, 6, 7 and 14
Open Access
- 1 May 1961
- journal article
- Published by Oxford University Press (OUP) in The Journal of Immunology
- Vol. 86 (5) , 567-574
- https://doi.org/10.4049/jimmunol.86.5.567
Abstract
Summary: Adenovirus types 5, 6, 7 and 14 were studied with respect to the quantitative reaction with antiserum, the length of the latent period of the initial multiplication cycle, and the production of infectious virus per HeLa cell; the results of the experiments were compared with similar studies done with adenovirus types 1–4. Types 5 and 6 were found to be similar to types 1 and 2 and types 7 and 14 were similar to types 3 and 4. These studies confirm earlier data which indicated that adenoviruses could be subdivided into at least two subgroups by certain biologic characteristics. In addition, it was demonstrated that adenovirus types 5, 6, 7 and 14 were quite stable for at least 1 week when stored at 36°C at pH 6.5 and pH 7.5, and that these viruses dissociated poorly from infected HeLa cells. These properties are similar to those determined for adenovirus types 1–4.Keywords
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