Endothelial Cell Membranes: Polarity of Particles as Seen by Freeze-Fracturing
- 12 January 1973
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 179 (4069) , 190-192
- https://doi.org/10.1126/science.179.4069.190
Abstract
Freeze-fracturing shows particles within membranes. In plasma membranes of most cells the particles are more strongly bound to the inner half. In unfixed endothelial cells, this polarity is reversed. Glutaraldehyde fixation results in conventional polarity. The reverse polarity may be related to a mechanism for preferential fusion of pinocytotic vesicles with the plasma membrane.Keywords
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