Entzündungshemmende Sesquiterpenlactone vonAchillea setacea*
- 1 October 1991
- journal article
- abstracts
- Published by Georg Thieme Verlag KG in Planta Medica
- Vol. 57 (05) , 444-446
- https://doi.org/10.1055/s-2006-960146
Abstract
From the aerial parts of Achillea setacea W. & K. (Asteraceae) the main sesquiterpenes were isolated. Their structures were determined by means of 2D-NMR and MS as 11,13-dehydrodeacetylmatricarin (1) (=14-deoxylactucin), rupicolin A (2), and rupicolin B (3). These are the first compounds with an α-methylene-γ-lactone structure isolated from a species belonging to the Achillea millefolium aggregate. Achillicin, achillin, 8-hydroxyachillin, 8-acetoxyachillin, and matricin could not be detected in A. setacea. For both rupicolin B and 11,13-dehydrodeacetylmatricarin an anti-inflammatory activity was found in the croton oil ear test.Keywords
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