Management of Spasticity in Cerebral Palsy with Botulinum-A Toxin: Report of a Preliminary, Randomized, Double-Blind Trial
- 1 May 1994
- journal article
- clinical trial
- Published by Wolters Kluwer Health in Journal of Pediatric Orthopaedics
- Vol. 14 (3) , 299-303
- https://doi.org/10.1097/01241398-199405000-00005
Abstract
In order to evaluate further the efficacy of local intramuscular injections of botulinum-A toxin (BAT-A) in the management of dynamic equinus deformity associated with cerebral palsy, a randomized, double-blind, placebo-controlled study was undertaken. When evaluated using our Physician Rating Scale, 83% (five of six) of patients receiving toxin showed improvement, versus 33% (two of six) receiving placebo. There were no major complications. BAT-A injections appear to be safe and effective in children, and merit further prospective study.Keywords
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